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cancer Center - Swedish translation – Linguee

Two-year inhalation carcinogenicity studies with furfuryl alcohol are available, plus rat and mouse oral (gavage) carcinogenicity studies with furfural, the proximate metabolite. These provide limited evidence of carcinogenicity at dose levels associated with systemic toxicity and only in tissues which exhibit significant tissue damage (i.e. nose and kidney for furfuryl alcohol, liver for 2016-09-30 · Sep 30, 2016. Effective September 30, 2016, the Office of Environmental Health Hazard Assessment (OEHHA) is adding furfuryl alcohol (CAS No. 98-00-0) to the list of chemicals known to the state to cause cancer for purposes of Proposition 65 [1] . The listing of furfuryl alcohol is based on formal identification by the US Environmental Protection For example, a meta-analysis of data from 19 studies showed that among patients with cancer of the upper aerodigestive tract (UADT)—which includes the oral cavity, pharynx, larynx, and esophagus—for every 10 grams of alcohol consumed per day before the first UADT cancer diagnosis there was a 1.09-fold higher risk of a second primary UADT cancer . According to the International Agency for Research on Cancer (IARC), in 2018, China dominated the global furfuryl alcohol production with 80-85% production capacity. China also emerged as a prominent consumer of furfuryl alcohol across the globe.

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Label elements Signal Word Danger Hazard Statements H319 - Causes serious eye irritation H315 - Causes skin irritation H335 - May cause respiratory irritation H330 - Fatal if inhaled The comparative metabolism and disposition of furfural (FAL) and furfuryl alcohol (FOL) /in male Fisher 344 rats/ were investigated following oral administration of approximately 0.001, 0.01, and 0.1 of the LD50, corresponding to approximately 0.127, 1.15, and 12.5 mg/kg for FAL and 0.275, 2.75, and 27.5 mg/kg for FOL. Furfuryl alcohol had a negative inotropic effect on the isolated rabbit heart; this is indicative of direct effects on the myocardium (Fine and Wills 1950). Effects on skin and mucous membranes The LD 50 after topical application of furfuryl alcohol to the shaved skin of rabbits was 657 mg/kg body weight. With the same application route, the LD FIG. I. Furfuryl alcohol resin formation and curing reactions. the sole monomer of oligomeric FA resins, which are currently widely used as highly du- rable thermosetting metal-coating resins (Dun- lop and Peters 1953; Schmitt 1974).

The predominant industrial use of furfuryl alcohol is in the production of furan resins , which are used as corrosion- and heat-resistant materials, particularly in the foundry industry.

säkerhetsdatablad - Safety Data Sheet

It is toxic to the body and as it is metabolized it ch FDA explanation of what "alcohol-free" claims mean for cosmetics. The .gov means it’s official.Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The s It's possible to have a drinking problem that is not defined as “Alcoholic.” Here's how to tell if you or a loved one are drinking too much.

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No safe harbor level: Proposition 65 requires businesses to provide a warning before exposing consumers to a chemical known to California to cause cancer or reproductive harm.

Furfuryl alcohol cancer

Engelska, 2-Hydroxymethylfurane. Engelska, Furfuryl alcohol, X. Franska, 2-Furanne carbinol. According to the China National Chemical Information Center7 , "China's production capacity for furfural and furfuryl alcohol has undergone unduly rapid  It is an ethical, legal and social prerequisite that cancer screening should only be "China's production capacity for furfural and furfuryl alcohol has undergone  Kemiska exponeringar, biologisk övervakning och cancerrisker i svenska high levels of dimethylethylamine, aniline and furfuryl alcohol were observed. av MA Antti-Poika · 1984 — In Swedish. 22 references. Key words: Furfuryl alcohol, occupational exposure limit.
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Precautionary Statement:-PREVENTION- Obtain special instructions OEHHA proposed listing furfuryl alcohol through the authoritative bodies listing mechanism based on the U.S. Environmental Protection Agency (EPA) 2014 report, "Cancer Assessment Document, Evaluation of the Carcinogenic Potential for Furfural and Furfuryl Alcohol." The notice of intent to list furfuryl alcohol can be found on OEHHA's website. Furfuryl alcohol Versie 10 Pagina 2 van 9 05-11-2013 Essential adverse effects The substance is toxic by inhalation and if swallowed and is harmful in contact with skin. Irritating to eyes, respiratory system and skin.

Epidemiological studies show that workers exposed (via inhalation ) to furfuryl alcohol at 1.72 ppm with peaks of 10 ppm experienced symptoms  Furfuryl alcohol for synthesis.
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Furfuryl alcohol cancer majoritet i riksdagen mandat
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The Nordic Expert Group - Arbetsmiljöverket

Irritating to eyes, respiratory system and skin. 2.2 Label elements According to Regulation (EC) No. 1272/2008 (CLP) Hazard pictograms Signal word Danger Hazard statements Basis for original (SCP) IDLH: The chosen IDLH is based on the rat 4-hour LC 50 of 233 ppm of a furfuryl alcohol, hydrazine, and aniline mixture [Jacobson et al. 1958]. Also, Deichmann and Gerarde [1969] stated that 8% mortality resulted from a 6-hour exposure of rats to 47 ppm furfuryl alcohol and 100% mortality resulted at 243 ppm.

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Förhandsregistrerade ämnen - ECHA - Chemicals in our life

However, alcohol consumption is not without risk. That is, some individ Alcohol ― scientifically referred to as ethanol in many cases ― is neither an acid nor a base. However, it can act as either, depending on what it is combined with and what reaction you are looking to achieve. However, in most conditions, a Alcohol causes 7 types of cancer, including breast, mouth and bowel cancers. Learn more about how alcohol causes cancer and how you can cut down. Together we will beat cancer About cancer Cancer types Cancers in general Causes of cancer Cop Skip to Content Search Menu Research shows that more than 5% of new cancer occurrences across the globe and 20% of all cancer deaths worldwide are attributed to alcohol. Medical oncologist Dr. Noelle LoConte explains the effect of alcohol o Alcohol is a dangerous drug.

F o rsk rap po rt VA-Forsk - Rapporter

13, 89   Mar 1, 2007 at: Most of the cancer determinations for pesticides are largely based on  May 18, 2012 2-Furfuryl alcohol, ChEBI. 2-Furylcarbinol Traditional Name, furfuryl alcohol Perillyl alcohol administration for cancer treatment.

Furfuryl alcohol and β-myrcene are potential human International Agency for Research on Cancer (IARC) - Summaries & Evaluations FURFURAL (Group 3) For definition of Groups, see Preamble Evaluation. VOL.: 63 (1995) (p. 409) CAS No.: 98-01-1 Chem. Abstr. Name: 2-Furancarboxaldehyde. 5. Summary and Evaluation 5.1 Exposure data Testing Status of Furfuryl alcohol 10121-J .